Bit of an interesting part is, that we dont share hardware similarities, I'm on an intel based system, 16GB of RAM, windows 10 PRO (not home).
The intel part means we dont share motherboard series either, do you have a Creative Sound Blaster Audigy (PCI) sound card by any chance?
And as with you, it worked flawlessly on other comps I own. But this is my "main" rig so to speak, so bit of a headache.