An integrated threat protection solution designed to detect, investigate, and respond to cyber threats across Microsoft 365 services.
Yes. Microsoft Defender on iOS uses a local VPN for web protection, and iOS allows only one device-wide VPN to be active at a time. Microsoft also notes that some apps can have issues when a VPN is configured, and in those cases the Defender VPN can be disabled.
The supported workaround is:
- On the iPhone, open Settings.
- Go to General > VPN.
- Select the i button for Microsoft Defender for Endpoint.
- Turn off Connect On Demand.
That disables the Defender VPN while using the affected app or scenario.
Important: when the Defender VPN is disabled, web protection is not available. To turn it back on later, open the Microsoft Defender app and select Start VPN.
There is no documented iOS-specific workaround in the provided material that keeps Defender VPN enabled while avoiding the app impact. The documented approach is to disable Defender VPN when another app or VPN scenario is affected.