A family of Microsoft word processing software products for creating web, email, and print documents.
I've never had that check box ticked, and have often had the problem of files "read only". I think the issue lies elsewhere, something related to where the file originated, perhaps. I find the issue occurs too irregularly for me to work out what might be causing it.
On another point, Microsoft have obviously been doing a great deal of work with OneDrive of late, speeding up the process of uploading and downloading from their servers. I am now allowing my PC to save to OneDrive rather than to my PC, and the delay in opening and saving a document has at last become quite acceptable.