Using classic Outlook for Windows in business environments
So far, I cannot cause the GPU to spike. I tested switching mail to calendar and otherwise. Does this happen on the primary monitor or is it secondary or does it matter?
In the past when we looked into graphics issues engineers would get a DXDiag report, Which version of DirectX is on your PC? - Microsoft Support. This will show you the driver date which could help indicate if the driver is old and needs to be updated.
Another thing to test if it would help is the option File, Options, General, User interface options, Office support for high definition displays - Microsoft Support. Test with best appearance and optimize for compatibility.