I ended up having to completely uninstall the software for ES-400 and then the software for my printer. Then I restarted the computer, made sure that all information about either device was completely removed from my system, registry, everything. Then I got it to work by doing a new install and then blocking the pc from getting on the internet and then installed the ES-400 scanner completely. After I had made sure it worked, and that it couldn't update without my permission, I then installed the printer and blocked it from automatically updating.
I also created a restore point and I will continue to keep the auto update turned off because I believe that Epson would intentionally update it so that it wouldn't work in the future.