Hey everyone,
I have finally fixed this issue fixed on my PC. I'm so damn happy 😅
Changing my input from DisplayPort to HDMI resolved it. This fixes the crashing completely, even with two sticks of memory in dual-channel mode at full speed 3200Mhz.
This got me curious, since I saw that using HDMI limits my refresh rate to 100Hz. So, I switched back to DisplayPort but forced it to run at 120Hz instead of the full 144Hz. This also runs flawlessly with dual-channel memory and IMO confirms that 144Hz (combined with certain memory configurations) is somehow the causing the crashes.
I've ordered a new DisplayPort cable to see if it resolves the issue at 144Hz, but even if it doesn't I'll be happy with 120Hz since the 5600XT rarely gets above 120 FPS in games I play at 1440p anyway!
I hope this helps some of you.
EDIT: Sorry to hear about your new issue Tyler. I am on the latest Window 10 update and AMD drivers (I now have the full AMD Overlay etc installed) and have not run into that problem.
EDIT 2: New DisplayPort cable has the exact same issue at 144Hz. I can live with 120Hz so it's all good and no more crashes :)
EDIT 3: I other solutions posted online to get 144Hz working. Summary is here: https://evanshortiss.com/amd-driver-memory-lock-timeout