The problem is due definitely to Version 21H1 update.
I manage many PCs, some of the after upgrading goes BSOD during boot some other I did not have mic and hedphone any longer.
I did some test and I discovered that if you remove realtek drivers, systems boot correctly but you lose the ability to have an imput device and switch to a different output port.
Otherwise if you rollback the 21H1 upgrade everything comes back to normality and you have everything working.
Given this I strongly reccommend to upgrade to 21H1 only when a reliable audio driver will be proposed by realtek or (better) Microsoft itself.
Al the tests I made are done on x64 version and 6 PC/Latops ranging form 10 to 1 years old.
You see with smart working a pc without audio is nearly useless.