Hi @fg2001,
I just turned on Core Isolation\Memory Integrity and restarted. It remained on. This is an Hyper-V VM installation ( 2nd-gen ).
If I try to turn on Core Isolation\Memory integrity in an MBR installation, it cannot be turned on. I receive a message box reading "There is drivers incompatibility and I should rectify it before I try to turn the feature on." or something to that effect.
Looks like with Hyper-V they can emulate anything, but I wonder how much of a validation test is running in VM instead of a real machine? π