I have the same problem.
I bought my Surface Book 2 in April 2018. And connected it to my existing Samsung UE590 UHD 4K monitor with no problem. I was using a Microsoft HDMI-to-USB-C adapter.
But a few days ago, I had the Surface Book 2 doing a 3D render, disconnected from the Samsung. And I connected my Surface Pro 3 to the Samsung to work on other things. When the render was done, I reconnected the Surface Book 2. And the flickering began. I've switched both Surface devices on the Samsung before with no problem. But the fact that the problem started after a switch is very odd.
BTW, the Surface Pro 3 still connects to the external monitor. And works as expected.
I've connected the Surface Book 2 to my Sony TV. The flickering happens there too. So, the Surface is clearly the problem.
I have the latest updates, including drivers. And have exhausted the different troubleshooting methods suggested by Microsoft. Nothing fixes the problem.
I'd really appreciate any help.
Thank You.