A family of Microsoft server products that support large-scale implementation management of enterprise application integration processes.
Make sure to Download Host Integration Server 2020 Cumulative Update 1 from Official Microsoft Download Center install that and reboot.
If that still doesn't fix the issue, raise an issue with Microsoft, and ask them for HIS2020-Server-BTSAdapters-KB5046904-x64-EN
This caused the Receive Locations to start having the same issue, changing the Host CCSID to 1208 in the connection string resolved this.