Dear Michael,
Unfortunately, as a forum moderator, I am not able to access your server or its logs to diagnose this directly. My role here is limited to general guidance you can apply from your side. The MMC error is almost certainly secondary. Exchange Toolbox runs over Exchange PowerShell, and when that session fails the exception cannot be serialized back to the snap-in, producing the message you are seeing. That is why DISM, SFC and clearing the MMC config made no difference. Given the drive filled just before this started, I would recommend checking the following:
- Run
Test-ServiceHealth, or check services.msc for any Microsoft Exchange service set to Automatic that is not running.
- Confirm the Default Web Site and Exchange Back End are started in IIS, and that the PowerShell virtual directory exists under both. Run
iisreset if they look correct.
- Open the Exchange Management Shell directly. If it also fails, the error will be far more useful than the snap-in's.
- Check the Application event log around the reboot, filtered on MSExchange sources.
- Run
Get-MailboxDatabase -Status to confirm the databases are mounted.
Worth noting separately that extending the disk treats the symptom. Transport queue growth or logs not being truncated are the usual causes, so the drive may fill again.
If you need to escalate, you can go through Microsoft Professional Support (pay-per-incident), with initial response times from 2 hours for critical business impact. For more technical or in-depth topics, the Home | Microsoft Community Hub offers a vibrant space to collaborate with Exchange Server specialists and IT professionals. This can be a helpful step before considering a paid support option.
I hope this information is helpful and provides you with a clear path forward. Should you have any further questions or need additional assistance, please don't hesitate to reach out. I'm always happy to help.
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