Please provide more information on what you mean by you computer has been locked up.
1
If there is a notification in your web browser about your PC being infected and there is a phone number on the alert, that is just a tech support scam.
Do not click anything on that page and do not phone any number on that page.
When this happens, open Task Manager (Ctrl + Shift + Esc)
On the processes tab, locate your browser and end task on that
You can then continue to user your PC and browse the Internet
2
Or if you are unable to get into Windows on your PC, what happened before you were locked out of your PC, did you make any changes or did you go to your account online and lock the PC, please provide full details and a screenshot of the problem.