451 4.7.650 The mail server [66.29.137.57] has been temporarily rate limited due to IP reputation.

The error 451 4.7.650 The mail server [66.29.137.57] has been temporarily rate limited due to IP reputation means Microsoft 365/Outlook.com is throttling mail from the sending IP because of a low or suspicious IP reputation. This is temporary rate limiting, not a permanent block, but it can cause long delays or eventual non‑delivery.

For a small non‑profit sending to Outlook.com/Hotmail/MSN recipients, the supported steps are:

1. Check whether the IP is blocked or only throttled
   • If non‑delivery reports ever show 550 5.7.606-649 Access denied, banned sending IP [66.29.137.57] with instructions to visit https://sender.office.com/, then the IP is on the Microsoft 365 blocked senders list. In that case, use the Office 365 Anti-Spam IP Delist Portal at https://sender.office.com to request removal from the blocked senders list, as described in the “External senders – Use the delist portal to remove yourself from the blocked senders list” article.
   • If the error remains 451 4.7.650 or 451 4.7.550 Access denied, please try again later, this indicates throttling due to reputation or suspicious activity from that IP. Microsoft temporarily restricts traffic while it evaluates the messages. Once evaluation is complete and the traffic looks clean, the restriction is removed automatically.
2. Improve IP and domain sending reputation Microsoft’s filtering (SmartScreen and related systems) uses IP reputation, domain authentication, complaint rates, list quality, and content signals.
   • Ensure SPF and other authentication records are correctly configured so that the sending IP is authorized for comaldarksky.org. Microsoft explicitly leverages SPF to validate that the sending domain is authorized.
   • Avoid any behavior that looks like spam or abuse: no purchased lists, no sending to harvested or guessed addresses, and no namespace mining (probing Outlook.com servers to verify addresses without actually sending mail). Namespace mining is explicitly disallowed and can cause IP action.
   • Keep complaint rates low: ensure recipients have explicitly opted in, include clear unsubscribe options, and promptly remove addresses that bounce or complain.
   • If using new or recently changed IPs, be aware that new IPs have little or no reputation and are more likely to see deliverability issues until a positive history is built. Ramp up volume gradually and maintain clean lists.
3. Check local/server-side factors that can hurt deliverability
   • If anti‑virus or security software on the mail server or firewall has features like “Internet Email Auto Protect” or “Internet Email Protection” enabled, disable those and test again. Misconfigured email scanning at the server level is noted as a cause of deliverability issues.
   • Confirm DNS is correctly configured for the sending domain and IP (including forward and reverse DNS, and consistent HELO/EHLO names) per the sender support guidance.
4. Use Microsoft sender support if the issue persists
   • If mail complies with Microsoft’s policies and guidelines and deliverability problems to Outlook.com/Hotmail/MSN persist, use the Outlook.com sender support channel for IT admins described in “Sender Support in Outlook.com” to contact support and request help investigating the IP reputation and throttling.
5. While throttled
   • The receiving side is already retrying for some time, as shown in the delay notice. If throttling is temporary and reputation improves, queued messages may eventually be delivered. If throttling continues for days and messages start bouncing permanently, treat it as a reputation/block issue and follow the delist and sender‑support steps above.

References:

• External senders - Troubleshoot email sent to Microsoft 365
• External senders - Use the delist portal to remove yourself from the blocked senders list and address 5.7.511 Access denied errors
• Sender Support in Outlook.com