The described behavior matches known issues where mouse input is effectively “captured” or blocked so that clicks only work in a specific window or desktop context. There are two relevant patterns in the provided material and both point to system-level bugs rather than a hardware fault:
- Mouse actions blocked across desktops / virtual desktops (Windows 8.1 / Server 2012 R2)
In earlier Windows versions, mouse actions could be blocked when creating or using a virtual desktop because mouse hooks were invoked across desktops. This caused clicks not to behave as expected in some windows or desktop contexts. Microsoft confirmed this as a bug and fixed it via a security update (KB3002885). - UI elements (Start button, charms, app controls) not responding (Windows 8.1)
Another confirmed bug caused the Start button and other UI elements not to respond to mouse input, while keyboard and touch still worked. Workarounds included restarting Windows Explorer or signing out and back in. Disabling certain corner navigation behavior reduced recurrence.
While those documented issues are for Windows 8.1/Server 2012 R2, they show that:
- Mouse input can be misrouted or blocked at the shell/desktop level.
- The system can end up in a state where keyboard still works but mouse clicks only work in limited contexts or not at all.
- Restarting shell components or forcing Windows to re-evaluate running apps/desktops (for example, via sign-out, restart, or update) can restore normal behavior.
In the scenario described:
- Only one window (or one app’s windows) responds to mouse clicks.
- Keyboard shortcuts (Windows key, Alt+Tab) still work.
- Initiating a restart, then canceling at the “apps preventing shutdown” screen, forces Windows to enumerate and interact with all open windows. After this, mouse input works normally again.
This is consistent with a shell/desktop input-routing bug similar in nature to the documented issues. The cancel operation during shutdown effectively acts like a partial shell reset: Windows re-queries and interacts with all top-level windows, which appears to break the stuck state and restore normal mouse routing.
Given the available documentation, the most closely aligned mitigations are:
- Force a shell reset when the problem occurs
Instead of fully rebooting, try the equivalent of the Windows 8.1 workaround:- Open Task Manager (Ctrl+Shift+Esc or Ctrl+Alt+Del → Task Manager).
- Locate Windows Explorer in the Processes list.
- Right-click it and choose Restart.
- Sign out and sign back in
- Use the Windows key to open Start.
- Use keyboard navigation to select the account menu and choose Sign out.
- Sign back in.
This resets the user shell and desktop session without a full reboot.
- Full restart if needed
- If the shell reset or sign-out does not help, perform a full restart. The behavior described (attempting restart, then canceling when prompted about unsaved work) is effectively a variant of this that happens to reset the problematic state.
- Keep system fully updated
Since similar mouse-blocking issues were fixed by cumulative/security updates in earlier versions, ensure Windows 11 is fully updated via Settings → Windows Update → Check for updates.
The behavior described is consistent with a system bug in input routing rather than a Logitech device or driver problem. The practical recovery steps, based on documented similar issues, are to restart Windows Explorer, sign out/in, or restart the system, and to keep Windows updated so that any underlying shell/input bugs are addressed by future fixes.
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