how to fix publisher not opening

Try these steps in order to fix Publisher not opening and the repair prompt not doing anything:

1. Make sure Office/Publisher is up to date
   1. Open any other Office app that still works (for example Word or Excel). If none open, skip to step 3.
   2. Go to File > Account (or Office Account).
   3. Under Product Information, select Update Options > Update Now.
   4. Let updates complete, then try opening Publisher again.
2. Check if an add‑in is blocking Publisher
   1. Start Windows Run (press Windows key + R).
   2. Type mspub /safe and press Enter to start Publisher in Safe Mode.
      • If Publisher does not start in Safe Mode, go to step 3.
   3. If Publisher opens in Safe Mode, select File > Options > Add‑Ins.
   4. In the Manage box at the bottom, choose Publisher Add‑ins (or COM Add‑ins) and select Go.
   5. Clear the check box for one add‑in and select OK.
   6. Close Publisher, then start it normally (without /safe).
      • If it opens, the last add‑in unchecked is causing the issue. Leave it disabled or remove it.
      • If it still fails, repeat the process, disabling add‑ins one by one (including any COM Add‑ins) until Publisher opens normally.
3. Run a full Office repair Because the built‑in “Repair now” from the error dialog often only runs a Quick Repair, run a full repair from Windows instead: Windows 11
   1. Select Start > Settings > Apps > Apps & features.
   2. Find the Microsoft Office / Microsoft 365 entry, select the More icon, then Advanced options (if available).
   3. Use Repair first; if that does not help, use Reset.
   4. If those options are not available or do not fix it, open Control Panel → Programs > Programs and Features.
   5. Right‑click the Office product and select Repair, or if not available, Change, then follow the on‑screen steps.
   Windows 10
   1. Right‑click Start and select Apps and Features.
   2. Select the Microsoft Office product and choose Modify.
   3. When prompted, choose Online Repair > Repair (this is the full repair). Follow the prompts and let it complete.
4. If repair still does nothing If the in‑place repair still does not run or Publisher continues to fail, fully remove Office and reinstall:
   1. Uninstall Office from Apps & Features or Programs and Features.
   2. Manually delete any remaining Office folders under C:\Program Files and C:\Program Files (x86) that clearly belong to Office/Publisher.
   3. Restart the PC.
   4. Reinstall Office/Publisher from the Microsoft account or installation media, then try opening Publisher again.

If Publisher opens only in Safe Mode even after repair, keep all add‑ins disabled and then re‑enable only those that are required, one at a time, to find the problematic one.

References:

• I get a "stopped working" error when I start Office applications on my PC
• 2 - Disable add-ins manually
• "Something went wrong" error when you try to start a Microsoft 365 app
• Windows 10
• Solution 2 - Repair Office from the Control Panel
• how i can fix the microsoft app problem - Microsoft Q&A
• How can I get office 365 to work? - Microsoft Q&A
• Office 2021 desktop apps fail to open, cannot restore or uninstall - Microsoft Q&A