Dear @Kevin Wing,
Welcome to Microsoft Q&A Forum!
Based on your description, I have tried my best to research it and I found that this behavior may occur in OneNote for Mac when the local app gets into a corrupted UI or cache state. Several users have reported identical symptoms such as copy/paste not working and text regions not being selectable. Here are several reasons that may cause it:
- A corrupted local OneNote cache
- A notebook stuck in partial‑sync state
- UI rendering bugs in recent Mac OS builds
- Too many notebooks open simultaneously
Therefore, you can try a few quick checks to narrow down the issue:
1.First, please try OneNote for the web via portal.office.com
If copy/paste works normally there, please use the web version as a temporary workaround while we troubleshoot the desktop app.
2.For the OneNote app on Mac:

3.Also, I ran a test on my Mac using OneNote version 16.105.2, and copy/paste works normally. To make sure you’re running a clean installation, please reinstall OneNote by downloading it directly from the Microsoft website. Avoid installing it from the Mac App Store, please follow the steps below:
- Go to Applications > select Microsoft OneNote > choose Move to Trash.
- Download Office directly from Microsoft website instead.
You can see this link for more details for it: Download, install, or reinstall Microsoft 365 or Office 2024 on a PC or Mac
4.If the issue still persists:
As a workaround, please try copying the content into Notepad (or any plain text editor) first, then copy it again from there into OneNote. This often bypasses formatting or rendering issues. Please consult a partially similar case as your situation: Copy & Paste From OneNote Issue
I hope this information can give you some insights and please feel free to update to me in comment section. Wish you a good day!
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