Actually Word updated in March and the reading voice now includes inflection.
I suppose I would not mind the inflection if it were to at least reflect upon the context of what is being said. Like some others in here, I write books, and having that "valley girl" inflection is entirely inappropriate to the context.
On the other hand, if MS is putting so much attention into this new Copilot AI thing, that might be cool if it could analyze the context for any statements like "so-n-so said 'this' angrily, while whosits said 'that', happily." Otherwise, it should go back to no inflection, as this would be the best for the neutrality of the idea.
Furthermore, I would still say, if you're going to involve anything at all, it should be a choice so you can customize it your way.