A family of Microsoft spreadsheet software with tools for analyzing, charting, and communicating data
I have exactly the same problem, and similar in that no mouse drivers.
I find Excell is the only app that jumps to use 100% of my processing, i'e the cause of the lag.
I don't think it's the mouse, as when I switch to another app, everything acts normally..., until I return back to excel. A cup of tea usual is the best fix.