A family of Microsoft word processing software products for creating web, email, and print documents.
The file that you are getting back from your wife is probably opening in Protected View, which would be because under File>Options>Trust Center>Trust Center Settings>Protected View, there is a check mark in the box for "Enable Protected View for Outlook attachments". Having a check mark in the box there for "Enable Protected View for file originating from the Internet" may also be the issue with the files that you are opening from OneDrive.
Do you have the OneDrive folder set as a Trusted Location under the Trust Center Settings?
Also, see the article "I keep getting files that I am working on locked for editing. Word only allows me to open them read-only” at: