A family of Microsoft word processing software products for creating web, email, and print documents.
Zoey: I can confirm that the problem still presents with Word 365 version 1703 Build 7967.2139.
The screen capture below shows a Word document in Print Layout view on the left, and how it appears when printed as a PDF on the right. The left boxed column was set with a CFF-OpenType Adobe Garamond Pro, 10pt & single spaced; the right boxed column is the Windows TTF OpenType Garamond 10pt, single spaced. When printed or made into a PDF, the left column does not match the Print Layout view as it should.
If you want to see for yourself, or test this with a different CFF-type of OpenType font, you can access the Word file here on OneDrive.