A family of Microsoft spreadsheet software with tools for analyzing, charting, and communicating data.
Hello John,
Welcome to Microsoft Community.
To resolve this issue we need more information. Let us know the following:
- Does this issue happen on all spreadsheets opened in Excel 365/2016 or a few?
- Have you checked if you are able to open new blank spreadsheets and tried moving between cells and copying large amounts of data to a new spreadsheet within the same workbook, while working on the new blank spreadsheets?
You may also check if this issue occurs while working in the clean boot mode on your computers.
Refer the article below to start the computer in clean boot:
http://support.microsoft.com/kb/929135
Note: The steps as mentioned for Windows 8 and 8.1 also apply for Windows 10.
After restarting your computer in Clean Boot mode open Excel 365/2016 and check if they work fine and you are able to move between cells and copy large amounts of data to a new spreadsheet with the same workbook.
If the issue resolves while working in the Clean Boot environment then follow the steps as mentioned under the heading ‘If you could not run a program before you performed the clean boot’ which is below the option What is next when I have a clean boot environment?
Important: Please refer to the section: How to reset the computer to start as usual after troubleshooting with clean boot of the Kb article to boot the computer in normal startup after fixing the issue.
Hope the above information helps. Please reply if you need further assistance.
Thank you.