To corroborate what Brian92101 has stated, this issue pertains, we've discovered and established, to higher resolution displays. Mine is WQXGA 2560 x 1600 1440p laptop display and the extra large icons/thumbnails are too small to be useful. As Brian stated, at FHD 1920x1080 res., icons/thumbnails look fine. Thumbnail size is even smaller, of course, at higher resolutions.
The following screen shots, both taken on the same laptop, demonstrate the problem: The first is taken at laptop's native resolution of 2560x1600. You can see that there are a total of 6 thumbnails running horizontally and 7 vertically. The second screenshot was taken with display set to 1920x1200 (my display has a 16:10 aspect ratio, Brian's is 16:9) and you can see that only 5 thumbnails run horizontally and 5 vertically. So, seeing fewer thumbnails means your seeing larger thumbnails. And, you know, they look larger.
Note that all the images in both screenshots are the same size, 2560 x 1600. Thumbnails should scale according to displays resolution.
Windows has a problem displaying properly sized icons/thumbnails at higher resolutions.