The hardlink target changes for every update.
For 10.0.22621.900:
C:\Windows\WinSxS\amd64_microsoft-windows-explorer_31bf3856ad364e35_10.0.22621.900_none_b3f510b242bd687a\explorer.exe
For 10.0.22621.963:
C:\Windows\WinSxS\amd64_microsoft-windows-explorer_31bf3856ad364e35_10.0.22621.963_none_b3b7320842eb5c25\explorer.exe
Use the script here to reapply the registry setting after installing a quality update.