I am NOT sure if using compatibility mode affects use of the H&R software or not, but here's how to use it for any older program...
Find the program file (the .exe the shortcut points to) in Windows Explorer. You can right-click a shortcut to see the path of this file.
Right-click on the file name, select Properties (you may or may not have to confirm Administrator mode), click Compatibility tab, select "Run this program in compatibility mode" and select Windows version. From this dialogue box, you can also run the Compatibility Troubleshooter to see if an old program can be run in Windows 10.