A few people don't have locked threads.
So, folks, for everybody tired, and also to help finding the origin of the CR0-manipulating rwx shellcode, can you please turn on the Core Isolation in control panel (and reboot)? Just put the switch to "enabled" (backup your most important data before that, perhaps). It does not remove the root cause, but it will shield the kernel, stop the rwx shellcode (with the culprit cr0-manipulating sequence), and because of that, hopefully stop the BSODs.
Dual boot users (with Linux): you can still have Core Isolation without secure boot if it needs be, by setting "RequireMicrosoftSignedBootChain" to 0 in Computer\HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\DeviceGuard. Essentially you break the requirement of having the signed secure boot chain (because you want to keep your Linux). Core Isolation will then run anyway while hoping that your bootloader wasn't compromised.
Core Isolation needs VT-d enabled in the BIOS menu. On older PCs, that setting might be off per default, and you need to go into the BIOS menu yourself. On all modern (even gaming) PCs, it will be on per default. It has become de-facto standard.
If Core Isolation demands to remove some drivers, do it. Sometimes it's a tedious search. If they are OEM drivers, you can also go to the official OEM site and get an up-to-date version, which has the critical bugs and flaws removed (the cause why Core Isolation rejects them.) The new OEM driver will be accepted then. If not, pretty sure your OS can live without them, probably better than before. On the bad side, the shielding costs: Core Isolation may eat one or two FPS and certain functionality like overclocking, undervolting, controlling fans from OS side (you can still do all that from BIOS).
Removing drivers can be done with autoruns.exe from the MS sysinternals suite (under 'drivers' tab, as admin, by unchecking the drivers or even deleting the entry). Or by deinstalling the associated software. You also need to reboot (without these drivers). Core Isolation will tell if you were successfull.
Removing third party drivers that Core Isolation wants to be removed, may already kill your problem entirely, without having to run Core Isolation.
Please report back both in case if the BSOD vanishes or not.