Okay, so I updated to the latest Windows release, Version 20H2, Build 19042.870 and my Dymo LabelWriter 450 Turbo immediately started turning out blank labels. I headed for the Dymo website and was greeted with a message in big red scary letters describing the problem and how to fix it. I had to upgrade to their Version 8.7.4.48933 (this might be a downgrade for you though, depending) and it worked like a charm; fixed the problem immediately.
LabelWriter Fix For Blank-printing Problem . I also included a screenshot of my Windows 10 Pro version for clarification. Hope this helps!