@DanDScan - that is interesting that it made such a dramatic change. As the C: disk is the boot disk (and should always be treated as "non-removable"), I am surprised that any "autorun" functionality is used at all! Did you say that Kapersky scan recommended that change? A reference would be useful.
Altering the registry can be dangerous. It is best to use an official utility for "autorun" changes. This official Microsoft tool (autoruns) developed by Mark Russinnovich is very good, and a right click on entries will remove registry entries as required. This is especially useful for those hard to detect items/drivers/bloat apps that start up that you do not need, and also detects stranded items from faulty uninstalls (that can cause added delays as items are searched for during startup).
https://docs.microsoft.com/en-us/sysinternals/downloads/autoruns