I am having the very same problem on Windows 10 v1809 (LTSC). I think it began when I installed a new monitor with a different scaling (125%) compared to the other two (100%). Previously, when all of them were using the same scaling (100%), I don't think I ever experienced it.
In my case, I have been able to fix it on a per application basis. If I just leave the compatibility options of the application empty, the bleeding occurs. However, if I select the "Change high DPI settings" option, click on the "Override high DPI scaling behavior. Scaling performed by" checkbox and then select any of the options, the bleeding disappears.
Hope that helps.