Try enabling the mouse trail in Windows, it's a temp fix but almost works 100% of the time. Another thing that helped me beyond the driver on the first post is formatting using their latest image from the media creation tool. The most recent image has 0 issues for me at least on my 2080 Ti and other PC with a RTX 3080.
It appears there is light at the end of the tunnel. MS is working on enhancing the HDR feature on Windows 10 to another level. With that there should be massive improvements in the way its implemented and work with games and the OS (I HOPE). I've personally called MS and escalated this to one of their engineers. Hope is on the way, see article below.
https://devblogs.microsoft.com/directx/auto-hdr-preview-for-pc-available-today/