I did MS updates today hoping issue is resolved, it reinstalled KB4493509 and installed KB4495667.
ODBC connection issue is back.
KB4493509 not available for uninstall.
uninstalled KB4495667 and KB4493509 then was available for uninstall and I uninstalled it.
ODBC connection good again.
Maybe MS will fix for next month's update Tuesday... Don't hold your breath.