Why does my Onedrive.exe file disappear from the %appdata%\local\microsoft\onedrive folder?

Same here!

While I realize this isn't exactly a helpful response, it seems the issue just went away for me. OneDrive randomly came back and has been working for a few days now. I'm on build 18.116.0610.0002 and Windows 10 1803 build 17134.112. Windows update hasn't had anything useful in a month or so other than updates for Windows Defender definitions, so that isn't it. I'm not sure if it's a permanent thing, but just wanted to let people know that Microsoft may have finally fixed the issue. Not sure though.

Just in case anyone is wondering, I used a new Windows 10 Pro Build 1803 ISO to perform a fresh Windows 10 installation. This issue has returned within a 2 day period. I am relegated to copying the OneDrive.exe file back to my AppData OneDrive local folder again.

This is ridiculous.

Problem has been impacting me for weeks - think it may be related to a Window Fall Creator 1803 upgrade.

I have installed from OneDrive 18.111.0603.0004 and the problem still recurs.

It sure would be nice to get some Microsoft help for a product I'm paying for with my Office subscription

While I recognize this remains an ongoing issue, I have found the following is the easiest as well as the longest lasting fix of all that I have read up on. 

When you notice your Microsoft OneDrive shortcut is missing, realize your OneDrive has stopped syncing - no longer loads with windows or you get a missing error when you click on your folder, follow these instructions. 

Make sure you can view hidden files. 

Go to C : 

Go to Users

Go to your user profile

Go to AppData

Go to Local

Go to Microsoft 

Go to OneDrive

Go to the folder with the most recent build. 

Final the OneDriveSetup.exe file and double click - run it right from this location. 

(Do not remove or do anything your existing OneDrive)

When I do this it will go through a quick install. No data is lost this way and it works perfectly as though nothing ever happened afterward. It also avoids you needing to uninstall or do anything else.

Note - 

This is the only fix I have been able to find. I do have to point out that any ideas to use uninstall and reinstall most likely will not work. When I was looking into this, I even went to the extent of formatting my entire pc and doing a full reinstall of my windows. (I allowed the new Windows 10 install to load the most recent version automatically.) This lasted about a week before it went back to disconnecting. 

As everyone else has said, this is terrible that we are forced to do research like this and they need to find out the issue and fix it! Especially considering this is a paid service. 

P.S. I did find the use of Microsoft Store App version and website version remain unaffected. I would use the Store App, however, it is very unfriendly when it comes to cutting-pasting and moving things around which I like to do with the PC Exe version of Onedrive. 

Hope this helps someone anyway.