Windows 10, multi Monitor, maximized window blank/empty space on top of screen

Indeed that the graphics driver reset isn't going to work for many. It's not even a fix in any common understanding of the term.  You're just purging the system of cached information that over time will re-establish and the issue will reoccur. Disabling protected view is a risk that no one should be taking in order to correct a scaling error within the OS. Especially a company that potentially has customers personal and professional information on stored databases. It's a vulnerability ripe for attack from a bad actor.

I know personally if I were the IT point man at a company I would avoid that workaround like the plague and the staff would have to suffer through the unsightly issue in order to maintain integrity of the protections in place to keep customer information secure. As for private home users that don't have that level of responsibility on their own systems this can be helpful as they don't have so much to worry about from outside attackers. They tend to focus more on companies than individuals as there's a larger "payout" (if you will) to attack a company. 

Microsoft does need to address this issue. Specifically if they have professional users on devices that can be used to gain access into further infrastructure containing customer details using that workaround. If one company is using this workaround (speaking of disabling protected view in specific) then we can naturally assume many others are as well. This could end up being a major security flaw because of the human desire for symmetry.

Just to say that i tried the “zoom to fit” option under the graphics card options, a solutoon i found on a previous link in this thread, and the problem went away so definitely that was a fix for me. Hope it works for others too, as it used tobhappen to me often and was wholly frustrating.

Thanks for offering that solution to me. I've tried that and unfortunately it failed to correct anything on my end. I've gone deep into the graphics card display settings, as well as the Windows 10 display settings and regardless of forcing resolution scaling, pushing the task from the CPU to the GPU or any other option available...nothing resolves the issue on my machine. I'm troubleshooting deeper within the OS to see if there's something I can do on my end to resolve this permanently but I'm not confident that I will be able to do much.

This flaw could be deeply seeded within the OS and therefore impossible for a user to correct on their own without dissecting code and editing the architecture. I have a lot of free time being furloughed at the moment but I'm not going to go that deep into the software when people who earn salaries far beyond mine are paid to do this. 

Considering that this thread has been going for years now and the issue is across numerous Windows OS builds ranging from 7-10. Certainly this is recognized by Microsoft. The only thing I want to know for certain is if they truly are working to remedy this issue or are they going to let it go until the next OS launch? And, will it even be fixed then considering the history of this issue?