Been one week since I have had a reboot. Saying that, I will probably have one soon. All these problems have arisen since the 1709 update, but improved since 16299.192.
An obvious change is, when someone logs out via shutdown or sign out, they disconnect but task manager shows them as still logged in but disconnected. It also shows some CPU usage and memory use for the signed out user. Not sure if it is associated with the reboot.