The latest version of USBOverdrive did work for me. It got the buttons on my Intellimouse Explorer working again.
El Capitan and Microsoft Mouse (IntelliPoint) Not Working
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Anonymous
After installing the El Capitan GM, the forward/back buttons (side buttons, 4 & 5) on my Microsoft Wireless Mouse 5000 are only registering as left mouse buttons. The most recent driver, Microsoft Mouse 8.2 is installed and shows up in the System Preferences, but appears to not be functioning. MicrosoftMouseHelper is in the login items. Suggestions?
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Windows for home | Other | Devices and drivers
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Anonymous
2015-10-04T15:22:42+00:00 -
Anonymous
2015-10-05T08:17:46+00:00 Works like a charm. Thanks!
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Anonymous
2015-10-05T20:16:42+00:00 I just tried this step by step. I reinstalled Intellipoint, rebooted, but El Capitan still does not see the mouse:
I have a Wheel Mouse Optical that has worked great on every Mac I've had, and OS X, for uncountable years :)
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Anonymous
2015-10-05T20:27:09+00:00 For those of you this didn't work for, maybe try this Terminal command?
csrutil disable
If it doesn't help, be sure to run this one afterward when you reboot again:
csrutil enable
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Anonymous
2015-10-05T20:57:47+00:00 The first way *may* have worked, but I tried the second way listed above, and it worked but only after I unplugged the mouse from the USB port and plugged it directly into the MacBook. Once it saw the Mouse (1 sec) I unplugged it and got the same graphic showing "no mouse". I plugged it back into the usb port where it has sat for years, and it showed right up.
So anyone with this issue, try Matt's steps from the Oct 1 post, and only try the second option later. And either way way make sure the mouse in question is plugged directly into the computer for the purposes of detection.