I have Sierra v 10.12.1
Microsoft IntelliMouse Optical USB / PS2 Compatible 5-Button
First Download Newest Intellimouse Software
https://www.microsoft.com/accessories/en-sg/d/intellimouse-optical
Install Driver (Security Permissions Most Likely Will Not Let You Open Driver)
Go To System Preferences > Security & Privacy > Bottom Right Click Open
Install Drivers (Mouse Will Still Not Be Detected, That's Okay)
Reboot Will Happen After Install
When Apple Logo Shows Up > Hold Down Command + R
This Will Take You To Safe Boot > Open Terminal
In Terminal Type > csrutil disable
Restart
Now Go To System Preferences > Open Microsoft Mouse
Mouse Should Be Detected.
Once You've Confirmed Mouse Detected > Restart Into Safe Boot Again (Holding Command + R At Apple Logo)
Open Terminal Again > csrutil enable
Should Be Good To Go!
