Please mention what version of Windows you are running, including whether it is 32/64-bit.
Please post the exact make and model of your computer.
There have been some very serious problems reported across the Internet with the October 2013 Microsoft USB software updates on certain Dell and Toshiba computers (... and possibly more makes. I have not read the entire Internet today).
Many sites cite October 2013 Microsoft Updates KB2862330 and/or KB2862335 because they change previously-working USB drivers to pig swill.
Symptoms I have read about (but not experienced) include problems with Keyboard, Mouse, PC Video Cameras, Digital Cameras, Soundblaster, USB sticks, backup devices and Skype. The most serious issue reported is where the PC will not boot.
(PA Bear, please stay off this thread)