My version of this problem (and thanks to all the previous posters for their efforts)
I just have to restart the computer. Not log off log on actually restart. Then it's ok for a while (hours, days) and then "cannot communicate with scanner" and repeat repeat
I think I've tried all relevant suggestions above.
Using services.msc then stopping and then starting the Epson Scanner Service does the trick - is there any way of creating a desktop shortcut to do this so as to permit the less savvy in the house to do this.
Thanks
win7 pro epson xp-402 usb connection