I was having the same problem with my wife's computer, which came with Windows 7 Home. I originally thought it was a problem with the video card, replaced the Geforce card with a Radeon card, updated to latest drivers, etc etc. I ended up buying her a different computer and taking over this one.
We got hit by lightning and fried the NIC, so I replaced the motherboard with the same one (except it's Revision 6.0 instead of 5.0), I wiped the hard drive, installed a copy of Windows 8.1 I had, same problem. Ran the upgrade to Windows 10, same problem. Updated to all Windows 10 drivers for the motherboard (made sure onboard video was disabled on the new mobo), the vid card, etc, etc. Same problem.
Out of curiosity, I moved a little 24" Smart TV over to my desk and plugged in HDMI because I was using 2 different older monitors that only supported DVI. Problem solved, been running it for a day now and haven't had the drivers crash or "application blocked" error a single time.
So try a newer monitor with HDMI if you are still having problems...