I have had my PC for a year or so now, and use CCleaner once, if not twice a week, yet I still get this issue.
I have a pretty nice Desktop PC running Windows 8.1 and my PC will almost lockdown for 5-10 minutes while ntokrnl.exe is hogging memory. This happens multiple time per day, maybe once or twice over the course of 2 hours of working.
This is EXTREMELY abnoxious, and I didn't pay to have a nice PC and windows 8 to get slowed down by a bug in windows eight.
Sorry went on a rant for a second. Anyways, just wanted to tell you that using CCleaner to clear your registry only helps me for about 4-5 hours working. Then the problems arrouses again.
Note: Ignore spelling or gramarricle issue. I am extremely dyslexic (not using it as an excuse) I am pretty good when it comes to typing, but go easy on me.