I don't know if this helps anyone or is applicable to Windows 8, but I have Win 7 running at 2560 x 1600 on a 30" display and found both IE and Chrome to be terribly blurry.
I am set for 150% scaling (understandably necessary for that resolution) which tells me that's 9pt Segoe UI at 144dpi- the recommended max.
I found a post which recommended ticking the "Use Windows XP style DPI scaling" under display settings, set custom text size. Selecting this has made a big difference with text very visibly clearer.