Interestingly enough, I installed the Google Chrome Frame add-on for Internet Explorer 10 some time ago and today, when I ended up on YouTube, I noticed that there wasn't any anti-aliasing effect affecting the text and it was just like we all want it to be all the time. Unfortunately this isn't a solution for all websites but it's good to see and proves that Microsoft's rendering method isn't a problem only when you don't have eyes to see the difference.
I think you can force Chrome Frame to be used on all sites by either prefacing URLs with cf: or with a setting in Chrome Frame (also a registry entry for the setting):
http://www.labnol.org/software/force-google-chrome-in-internet-explorer/9998/