Try rebooting after each change, especially the wireless. Are you pulling a USB receiver to disable the mouse? Is it in a powered USB hub? If so, perhaps you should also try repowering that?
Yes I tried rebooting after each change as that's the obvious thing to do. No its not a hub.
Check to see if that was enough of a hardware reset to just let you continue the boot. Otherwise what happens?
After booting into safe mode using the disc I can confirm that my PC works again how ever this does not solve the problem because in my line of work a problem is solved when you can switch it off and on as you pleased i.e. you know what caused it and how to prevent it.
I think it may help if you clarify what you are seeing as a result of your "added safe mode to the boot options so on start up every time I an choose normal mode or safe mode". What I was expecting you would see from my suggestion was a new panel with a Change Options link at the bottom. And from there you could choose what to do, the default being to just continue the first boot selection (e.g. the only one) normally, as if that menu had not even been shown.
What I see now is that rather than windows just booting all the way it will now stop and display like a which OS would I like to boot. With the default windows 8 and the added windows 8 safe mode.
The idea is it would clarify whether the device support was being provided by the boot manager (or UEFI) or whether the new OS would be responsible for the problem symptom.
If you read my first post I stated that I had the problem BEFORE I added safemode.
As I mentioned above, by booting into safe mode with the disc and then shutting down and rebooting the PC normally the issue appears to be gone... for now and this does not mean the problem is solved.