Kb is wired, mouse is wireless. Tried removing one and then the other but no change.
Try rebooting after each change, especially the wireless. Are you pulling a USB receiver to disable the mouse? Is it in a powered USB hub? If so, perhaps you should also try repowering that?
I can confirm that with the disc I can get into safe mode, so where should I start looking?
Check to see if that was enough of a hardware reset to just let you continue the boot. Otherwise what happens?
I know of event viewer and where to find it but I haven't really used it so not sure where I should be looking
If it is just a hardware hang I'm not sure what you would see. Event viewer would be good for detecting crashes or perhaps other signs of driver failure. I suppose though that you might at least be able to see if the OS had detected the failed reboot, e.g. in terms of timestamped entries which were obviously created when you had the problem symptom but not associated with what you were doing then.
I think it may help if you clarify what you are seeing as a result of your "added safe mode to the boot options so on start up every time I an choose normal mode or safe mode". What I was expecting you would see from my suggestion was a new panel with a Change Options link at the bottom. And from there you could choose what to do, the default being to just continue the first boot selection (e.g. the only one) normally, as if that menu had not even been shown. The idea is it would clarify whether the device support was being provided by the boot manager (or UEFI) or whether the new OS would be responsible for the problem symptom.
HTH
Robert