Is the backup destination an external drive?
Also try checking your internal drives:
Hard drive Testing - Bootable CD:
If you have a new Seagate hard drive the very next thing would be to download Seagate's Seatools (the bootable CD) and check for bad sectors:http://www.seagate.com/ww/v/index.jsp?locale=en-US&name=SeaTools&vgnextoid=720bd20cacdec010VgnVCM100000dd04090aRCRD
For Western Digital drives use WdDiag: http://support.wdc.com/product/download.asp?lang=en
HD Tune:
Provides drive info and has an option to test your drive.
SpeedFan:
Monitors internal temperatures and has an online drive health analysis feature
(SMART tab) for hard drives. It will show how your drives
compares with other drives of the same make and model.
http://www.almico.com/speedfan.php
JS
Never be afraid to ask. This forum has some of the best people in the world available to help.