My last post indicated the problem was solved by moving the receiver from the rear of the Desktop computer to the front. NOT QUITE. Yes there was a big improvement. However every now and again the intermittency would appear and each time after banging down the mouse down on the desk,on one side, the problem would go. That indicated some poor connection. The most likely area of bad contact is at the batteries. I tried silver conductive paint on the contact springs, no real improvement. I dismantled the mouse (four screws hidden under the two slide strips) All the wire battery connections to the printed circuit were resoldered. Had great performance since.
Running on one battery is not the answer.
Software can cause problems but in general a jerky /intermittent movement can be considered as an unreliable wireless link, low or momentary loss of signal.
To summarise
Keep the signal strong with the receiver close to the mouse (reduces risk of interference)
Check for an internal intermittent connection as above and fix if necessary.
MICROSOFT take note.