Catalyst Control Centre: Host application has stopped working

This may be the solution you are seeking.

I recently removed the Vista Recovery Center malware from another one of our company laptops. It has ATI graphics installed. This malware hides most of the files on the PC in an attempt to fool you into thinking that your PC is really damaged like it is reporting. Removing the malware does not undo the hidden aspects. In Vista, the c:\Users*"your profile name (usually Owner)"*  folder contains the AppData subdirectory that the Catalyst Control Center needs to access in order to function. When this directory is hidden, then CCC cannot locate the necessary files to launch. To fix this issue, I use the following steps.

Navigate to c:\ and right click on Users. Select properties. Under the General tab, look at the bottom for the Hidden selection. If there is not a check mark in the box, place a check mark there. Hit apply, select yes to apply to all subdirectories. If you clicked ok, you may notice that it disappeared from the right pane once it finishes. It should still be listed under the tree on the left. Right click on it again. This time remove the check mark and apply to all subdirectories. Once it has finished, your files in the Users directory should reappear and Catalyst Control Center should function normally again. This has worked in all cases that I have encounterd so far. Hopefully this works for you as well..

This was one of the few times I hunter around the internet and found a solution I was able to execute and guess what... It worked!

You are a life saver, Mike. I have windows 7 and it was different. I had no "hidden" button, but I was able to click on a different tab and restore default settings and then there was a "hidden button. With some reservation I chose to hide everthing and then unhide and it worked. It took some time before my folders starting showing up in my libraries again but they are all back now. Thank you. I thought it was another total loss of files.

This helped me resolve my issue with my own idiocy last night.  Thank you Op. 

I made my user profile folder  hidden last night which caused this error to appear suddenly this morning. This fixed my problem perfectly.  Just to add i was using windows 7 when i caused my own issues.  So This will work in windows 7 if  you or someone did something similar as i did.