Confirm exact issue with a Defender update last night. Couple reboots and it finally resolved itself and installed the definition update.
You could also try kick starting it by manually installing def update:
https://www.microsoft.com/en-us/wdsi/defenderupdates
1349 was the one getting the error, but the next one 1358 updated just fine from W.U. :-)

B.T.W.
The MS Insider ISO 19043.867 still comes with the legacy MS Edge.
No big deal because the new MS Edge Chromium is the first thing they make you download after a clean install.
I expect they will fix that on the final MCT ISO release. :-)