Azure translator script was working now getting request not authorized because credentials are missing or invalid

I had a Translator script working. Suddenly the API started giving response

 {  "error": {
    "code": 401001,
    "message": "The request is not authorized because credentials are missing or invalid."
  }
}

Here is the relevant code:

key = "****"
endpoint = "https://api.cognitive.microsofttranslator.com"
location = "global"
path = '/translate'
constructed_url = endpoint + path
params = {'api-version': '3.0', 'to': 'en'}
headers = {
    'Ocp-Apim-Subscription-Key': key,
    # location required if you're using a multi-service or regional (not global) resource.
    'Ocp-Apim-Subscription-Region': location,
    'Content-type': 'application/json',
    'X-ClientTraceId': str(uuid.uuid4())
}
update_query = "update pulsar set translated_content = %s where id = %s"
select_query = "SELECT id,dewindowfy_content,cld3_lang from bri where dewindowfy_content is not null and cld3_lang ~ 'id|ms|fil' and dup_of_pulsar_unique_id is null and translated_content is null order by random() limit 5000"
@sleep_and_retry
@limits(calls=1, period=61)
def translate(texts,dbids,chars_translated,start):
    request = requests.post(constructed_url, params=params, headers=headers, json=texts)
    response = request.json()
    try:
        for item in response:
            text = item["translations"][0]["text"]
            dbid = dbids.pop(0)
            cur.execute(update_query,(text,dbid))
        conn.commit()
        return    
    except:
        print(json.dumps(response, indent=2))
        print('\nchars: {}'.format(chars_translated))
        end = time.time()
        dur = end - start
        print('secs: {}'.format(dur))
        rate = chars_translated * 3600 / dur
        print('chars/hr: {} \n'.format(rate))
        sys.exit()

I found some other threads on this error, which identified the problem as a missing Ocp-Apim-Subscription-Region parameter, but as you can see I have that and my Translator resource "essnentials" section confirms that my location is global. I tried regenerating the key, no help. What to do?