.NET: Microsoft Technologies based on the .NET software framework. Runtime: An environment required to run apps that aren't compiled to machine language.
System.Net.Http was reworked for net 4.6.1 and is part of the framework so you no longer include the package. you probably have a 4.6 project or nuget package that is dependent on the old package. You can fix up the projects or just a add a binding override in web.config
if it runs locally, than check the hint paths in the project files, they are probably out of date.